Naoum Issa, MD, PhD

Naoum Issa, MD, PhD

Neurology

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UChicago Faculty Physicians hold faculty positions with the University of Chicago and provide care for patients on the academic health system's main campus in Hyde Park and in care centers throughout the Chicago region. UChicago Faculty Physicians who provide services at UChicago Medicine AdventHealth Bolingbrook, Hinsdale, La Grange and GlenOaks hospitals are independent providers with privileges at those hospitals. Except as otherwise denoted, independent providers are not employees or agents of UChicago Medicine AdventHealth Bolingbrook, Hinsdale, La Grange and GlenOaks hospitals.

Expertise of Naoum Issa, MD, PhD

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Biography

Naoum Issa, MD, PhD, is board-certified in Neurology. His specialties include:

  • Epilepsy
  • Seizures
  • Care Philosophy

    Dr. Issa is passionate about offering advanced options for epilepsy that are resistant to anti-seizure medications. He works closely with his patients to control their seizures.

    He and his co-workers are continuing to develop ways to identify seizure footprints in deep brain structures without having to implant electrodes. Collaborating with other neuromuscular specialists, he is able to apply some of the same techniques used for seizure diagnosis to detect other neurological disorders.

    Awards & Recognitions
    A.B. Baker Teacher Recognition Award, American Academy of Neurology
    L.D.H. Wood Preclerkship Teaching Award
    Faculty Honoree; Alpha Omega Alpha - Beta Chapter
    American Epilepsy Association EpiPORT Fellowship
    Arnold P. Gold Foundation Humanism and Excellence in Teaching Award
    Alfred P. Sloan Research Fellow
    Areas Served
    Woodridge, IL | Chicago, IL
    Languages Spoken
    English
    Education

    University of Texas Southwestern Medical School

    Fellowships

    Clinical Neurophysiology at University of Chicago Medicine

    Neurology at University of Chicago Medicine

    Medical Organization Memberships and Committees

    American Academy of Neurology

    American Epilepsy Society

    Board Certification

    Epilepsy: The American Board of Psychiatry and Neurology, Inc. ABPN

    Neurology: The American Board of Psychiatry and Neurology, Inc. ABPN

    Publications

    Issa NP, Wu S, Rose S, Nordli D, Warnke P, Tao JX. Significance of small sharp spikes in mesial temporal lobe epilepsy. Clin Neurophysiol. 2024 Sep; 165:180-181. PMID: 39047670.

    Issa NP, Aydin S, Polley E, Carberry N, Garret MA, Smith S, Habib AA, Baumgartner NW, Soliven B, Rezania K. Intermuscular coherence as an early biomarker for amyotrophic lateral sclerosis: The protocol for a prospective, multicenter study. PLoS One. 2024; 19(5):e0303053. PMID: 38776297; PMCID: PMC11111088.

    Wu S, Issa NP, Rose SL, Haider HA, Nordli DR, Towle VL, Warnke PC, Tao JX. Depth versus surface: A critical review of subdural and depth electrodes in intracranial electroencephalographic studies. Epilepsia. 2024 Jul; 65(7):1868-1878. PMID: 38722693.

    Baumgartner NW, Hill JP, Bhatnagar S, Roos R, Soliven B, Rezania K, Issa NP. Added load increases the peak frequency of intermuscular coherence. J Electromyogr Kinesiol. 2024 Jun; 76:102881. PMID: 38574588; PMCID: PMC11111328.

    Ciarrocchi N, Pose F, Videla CG, Del Carmen GarcĂ­a M, Goldenberg FD, Lazaridis C, Issa NP, Redelico FO, Mansour A. Novel EEG Metric Correlates with Intracranial Pressure in an Animal Model. Neurocrit Care. 2024 Jun; 40(3): Call918-930-PMID: 37940837.

    Issa NP, Warnke P. Interstitial laser ablation for epilepsy: beauty lies in the eye of the beholder. J Neurol Neurosurg Psychiatry. 2023 12; 94(12): Call973-974-PMID: 37852745.

    Issa NP, Aydin S, Bhatnagar S, Baumgartner NW, Hill J, Aluri S, Valentic CS, Polley E, Gomez CM, Rezania K. Intermuscular Coherence in Spinocerebellar Ataxias 3 and 6: a Preliminary Study. Cerebellum. 2024 Apr; 23(2): Call601-608-PMID: 37428409; PMCID: PMC10776817.

    Satzer D, Wu S, Henry J, Doll E, Issa NP, Warnke PC. Ambulatory Local Field Potential Recordings from the Thalamus in Epilepsy: A Feasibility Study. Stereotact Funct Neurosurg. 2023; 101(3):195-206. PMID: 37232010; PMCID: PMC11227660.

    Michalak AJ, Greenblatt A, Wu S, Tobochnik S, Dave H, Raghupathi R, Esengul YT, Guerra A, Tao JX, Issa NP, Cosgrove GR, Lega B, Warnke P, Chen HI, Lucas T, Sheth SA, Banks GP, Kwon CS, Feldstein N, Youngerman B, McKhann G, Davis KA, Schevon CA. Seizure onset patterns predict outcome after stereo-electroencephalography-guided laser amygdalohippocampotomy. Epilepsia. 2023 06; 64(6):1568-1581. PMID: 37013668; PMCID: PMC10247471.

    Issa NP, Aydin S, Bhatnagar S, Baumgartner NW, Hill J, Aluri S, Valentic CS, Gomez CM, Rezania K. Intermuscular coherence in spinocerebellar ataxias 3 and 6: a preliminary study. Res Sq. 2023 Apr 17. PMID: 37131794; PMCID: PMC10153384.

    Issa NP, Nunn KC, Wu S, Haider HA, Tao JX. Putative roles for homeostatic plasticity in epileptogenesis. Epilepsia. 2023 03; 64(3): Call539-552-PMID: 36617338; PMCID: PMC10015501.

    Wlodarski R, Seibert K, Issa NP, O'Brien-Penney B, Soliven B, Sarswat N, Appelbaum D, Rezania K. 99m Technetium-pyrophosphate bone scan: A potential biomarker for the burden of transthyretin amyloidosis in skeletal muscle: A preliminary study. Muscle Nerve. 2023 Feb; 67(2):111-116. PMID: 36222831; PMCID: PMC10092886.

    Creery JD, Brang DJ, Arndt JD, Bassard A, Towle VL, Tao JX, Wu S, Rose S, Warnke PC, Issa NP, Paller KA. Electrophysiological markers of memory consolidation in the human brain when memories are reactivated during sleep. Proc Natl Acad Sci U S A. 2022 11; 119(44):e2123430119. PMID: 36279460; PMCID: PMC9636913.

    14. Satzer D, Esengul YT, Warnke PC, Issa NP, Nordli DR. Source localization of ictal SEEG to predict postoperative seizure outcome. Clin Neurophysiol. 2022 12; 144:142-150. PMID: 36088217.

    15. Seibert KM, Lee W, Eid A, Espinal AE, Klein SA, Abumurad SK, Tao JX, Issa NP. EEG background frequency is associated with discharge outcomes in non-ICU hospitalized patients with COVID-19. Front Neurol. 2022; 13: Call941-903-PMID: 36147043; PMCID: PMC9487016.

    Brang D, Plass J, Sherman A, Stacey WC, Wasade VS, Grabowecky M, Ahn E, Towle VL, Tao JX, Wu S, Issa NP, Suzuki S. Visual cortex responds to sound onset and offset during passive listening. J Neurophysiol. 2022 06 01; 127(6):1547-1563. PMID: 35507478; PMCID: PMC9190746.

    Bruzzone MJ, Issa NP, Wu S, Rose S, Esengul YT, Towle VL, Nordli D, Warnke PC, Tao JX. Hippocampal spikes have heterogeneous scalp EEG correlates important for defining IEDs. Epilepsy Res. 2022 05; 182:106914. PMID: 35367692.

    Seibert K, Wlodarski R, Sarswat N, Appelbaum D, Issa NP, Soliven B, Rezania K. Progressive Multiple Mononeuropathy in a Patient With Familial Transthyretin Amyloidosis After Liver Transplantation. J Clin Neuromuscul Dis. 2022 Mar 01; 23(3):143-147. PMID: 35188911.

    Satzer D, Esengul YT, Warnke PC, Issa NP, Nordli DR. SEEG in 3D: Interictal Source Localization From Intracerebral Recordings. Front Neurol. 2022; 13: Call782-880-PMID: 35211078; PMCID: PMC8861202.

    Karthik G, Plass J, Beltz AM, Liu Z, Grabowecky M, Suzuki S, Stacey WC, Wasade VS, Towle VL, Tao JX, Wu S, Issa NP, Brang D. Visual speech differentially modulates beta, theta, and high gamma bands in auditory cortex. Eur J Neurosci. 2021 11; 54(9):7301-7317. PMID: 34587350; PMCID: PMC8630510.

    Lee S, Wu S, Tao JX, Rose S, Warnke PC, Issa NP, van Drongelen W. Manifestation of Hippocampal Interictal Discharges on Clinical Scalp EEG Recordings. J Clin Neurophysiol. 2023 Feb 01; 40(2):144-150. PMID: 34010227; PMCID: PMC8590709.

    Abumurad S, Issa NP, Wu S, Rose S, Taylan Esengul Y, Nordli D, Warnke PC, Tao JX. Laser interstitial thermal therapy for NPRL3-related epilepsy with multiple seizure foci: A case report. Epilepsy Behav Rep. 2021; 16:100459. PMID: 34235417; PMCID: PMC8249776.

    Wu S, Issa NP, Lacy M, Satzer D, Rose SL, Yang CW, Collins JM, Liu X, Sun T, Towle VL, Nordli DR, Warnke PC, Tao JX. Surgical Outcomes and EEG Prognostic Factors After Stereotactic Laser Amygdalohippocampectomy for Mesial Temporal Lobe Epilepsy. Front Neurol. 2021; 12: Call654-668-PMID: 34079512; PMCID: PMC8165234.

    Mera RM, Wu S, Recalde BY, Issa NP, Del Brutto OH. Epilepsy, interictal EEG abnormalities and hippocampal atrophy in patients with calcified neurocysticercosis: a population study in an endemic milieu. Epileptic Disord. 2021 Apr 01; 23(2): Call357-365-PMID: 33926860.

    Santos de Lima F, Klein S, El Ammar F, Wu S, Rose S, Tao JX, Issa NP. Rapid development of seizures and PRES in a COVID-19 patient. Epilepsy Behav Rep. 2021; 15:100436. PMID: 33688630; PMCID: PMC7931684.

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    Question: What locations does Naoum Issa, MD, PhD practice at?
    Answer: Naoum Issa, MD, PhD practices at Woodridge at 2363 63rd Street, Suite 104, Woodridge, IL, 60517, Chicago at 5841 S Maryland Ave, Chicago, IL and 60637. Learn more about Naoum Issa, MD, PhD at AdventHealth.
    Question: What is Naoum Issa, MD, PhD's specialty?
    Answer: Naoum Issa, MD, PhD specializes in Neurology. Learn more about Naoum Issa, MD, PhD at AdventHealth.
    Question: What conditions does Naoum Issa, MD, PhD treat?
    Answer: Naoum Issa, MD, PhD treats the following conditions: Adult Epilepsy Services, Deep Brain Stimulation, Dementia, Electromyography, Headache, Headaches and Migraines, Lumbar Puncture, Myelogram, Nerve Conduction Studies, Nervous System, Neuroimaging Studies, Neurological Evaluation, Neuropsychological Evaluation, Parkinson's Disease and Vagal Nerve Stimulation. Learn more about Naoum Issa, MD, PhD at AdventHealth.